- Agriculture Department
- Ayush Department
- Backward Classes Development Department
- Coastal Shipping and Inland Navigation Department
- Consumer Affairs Department
- Co-operation Department
- Cultural Affairs Department
- Election Department
- Electronics and Information Technology Department
- Environment Department
- Finance Department
- Fisheries and Ports Department
- Food and Civil supplies Department
- Forest and Wildlife Department
- General Administration Department
- General Education Department
- Health and Family Welfare Department
- Higher Education Department
- Home Department
- Housing Department
- Industries Department
- Labour and Skills Department
- Law Department
- Local Self Government Department
- Minority Welfare Department
- Non-Resident Keralites Affairs Department
- Parliamentary Affairs Department
- Personnel and Administrative Reforms Department
- Planning and Economic Affairs Department
- Power Department
- Public Works Department
- Sainik Welfare Department
- Scheduled Castes and Scheduled Tribes Development Department
- Science and Technology Department
- Social Justice Department
- Sports and Youth Affairs Department
- Stores Purchase Department
- Taxes Department
- Tourism Department
- Transport Department
- Vigilance Department
- Water Resources Department
- Woman and Child Development Department
